One of my hardest challenges as a dog owner is trimming the nails. I'm always nervous that I'll get the quick and that nervousness makes the dogs antsier. Not to mention how hard it is for me to exert enough pressure to clip a Great Dane's nails.
Zoinks breeder has been showing off how easy it is to dremel dog nails so I finally broke down and got the right bit and have been conditioning Zoinks to let me dremel her nails. This started slowly, first with the dremel off and then gradually increasing the speed (and noise) before ever touching the nails. I've now done a few sessions with her and it's gone amazingly well so we are now conditioning the others to it. To make a positive association with the dremel we use a lick mat smeared with peanut butter (make sure it doesn't have xylitol in it). Just use a small amount, smeared on the mat, and then chilled it goes a long way. You could also use plain yogurt, cheese, liver wurst or even canned dog food.